Biophysics Lecture

Molecular design - from proteins to networks, coupling computation and experiment

Tanja Kortemme, Professor, Department of Bioengineering, University of California, San Francisco,

We develop computational prediction and design methods and combine them with experimental investigations with two complementary goals: to advance quantitative understanding of biological processes and to engineer new and useful functions. This talk will focus on our recent progress towards (i) borrowing mathematical formulations from the field of robotics to predict and "reshape" protein conformations with atom-level accuracy, (ii) engineering new protein interactions and conformational changes controlled with light and (iii) predicting and systematically modulating the specificity of protein-motif interactions in cellular systems.

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For more information, please contact Phoebe Ray by phone at 6440 or by email at [email protected].